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APIs (Active Pharmaceutical Ingredients)
APIs (Active Pharmaceutical Ingredients) Companies (500+)
APIs (Active Pharmaceutical Ingredients) News
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News Women in Pharma: Empowering yourself and other women in pharma
In our new monthly series, we interview women from across the pharmaceutical industry and supply chain to discuss the importance of gender diversity in healthcare, the workplace, and beyond.
19 Sep 2023 -
News Highly Bioavailable Mineral Gluconates as APIs
Dr. Paul Lohmann® offers various Mineral Gluconates with API documentation - ASMFs and for Ferrous Gluconate a CEP - for the registration of a drug with the health authorities.19 Sep 2023 -
News Pharma Supply Chain People Moves
The latest appointments and promotions across the pharmaceutical supply chain.24 Jul 2023 -
News Bringing the pharmaceutical supply chain closer to home
The pharmaceutical supply chain has encountered numerous disruptions in the last few years, impacting procurement, manufacturing, packaging, and distribution operations within the pharmaceutical industry. Read about the rise in calls for near/resh...19 Jul 2023 -
News Novo Nordisk announces expansion of Hillerød API manufacturing facility
Novo Nordisk will invest 15.9 billion Danish kroner into the expansion of their existing API manufacturing facility.12 Jun 2023 -
News The HPAPI supply chain: why manufacturers should care about handling and transportation
An increasing number of drug development pipelines are turning towards the use of HPAPIs to target rare and ‘undruggable’ diseases. In this article, we talk to leading industry experts about how pharmaceutical manufacturers are adapting and...7 Feb 2023 -
News Sai Life Sciences opens new HPAPI manufacturing facility in Bidar, India
A new HPAPI development and manufacturing block is now open at Sai Life Sciences’ Bidar Manufacturing Campus, expanding the CRDMO’s capabilities in small molecule discovery and commercialisation.17 Jan 2023 -
News CordenPharma joins sustainability initiative to achieve Net Zero
The CDMO has joined the environmental initiative looking to align private sector companies with those aims upheld by the Paris Agreement to reduce global warming.5 Dec 2022 -
News Trend Report: The True Cost of API Price Rises
Download our Trend Report to discover what the current landscape of APIs and their pricing means for the pharmaceutical industry in the future.5 Dec 2022 -
News CPHI Frankfurt 2022: Innovator Interviews – Bioiberica
In this series of interviews, we speak to the companies on the CPHI Frankfurt show floor who are driving innovation in pharma for a better healthcare future. We caught up with Mónica Gómez Navarro (Marketing Manager Branded Ingredients), ...28 Nov 2022 -
News CPHI Frankfurt 2022: Innovator Interview – DSM Biomedical
At CPHI Frankfurt we spoke to Anne-Cecile Bayne, Global Science & Innovation Lead Pharma and Medical Nutrition, and Marc Hendriks, Vice President Strategy & Business Development, on their expertise in nitrosamines and business strategy at DSM Biomedica...23 Nov 2022 -
News CPHI Frankfurt 2022: Innovator Interview – CordenPharma
In this interview from CPHI Frankfurt 2022, we speak to Dr Michael Quirmbach of CordenPharma about his role as President and CEO and what CordenPharma is bringing to the pharma industry.15 Nov 2022 -
News Lukang Pharma has launched two new products: Tulathromycin and Levodopa
Shandong Lukang Pharmaceutical Co., Ltd is a leading bio-pharmaceutical enterprise in China.14 Nov 2022 -
News A Comprehensive Pharmaceutical Enterprise with Multi-Field
We are committed to the export of several API and intermediates, such as Azathioprine, Mercaptopurine, Ribavirin etc.25 Oct 2022 -
News CDMO - Health is a Joint Project: Connect to Frankfurt on-demand
In this Connect to Frankfurt session, Emanuele Agnese, Business Development Manager and Pietro Allegrini, R&D Director at Indena, present the ways in which a reliable manufacturing partner in the pursuit of better health outcomes for patients and pharm...11 Oct 2022 -
News Dr. Paul Lohmann® - Your Partner for high value Mineral Salts
With our expertise in the chemical and physical modification of Minerals and our customer-oriented philosophy, we are the ideal partner to turn your ideas into reality. Meet us at CPHI stand #110F50!27 Sep 2022 -
News Lonza adds X-ray powder diffraction to micronisation portfolio in Monteggio (CH)
Lonza expands solid-state characterisation services for polymorph and solid-state properties of APIs with the addition of X-ray powder diffraction to its portfolio.25 Aug 2022 -
News Connect to Frankfurt - Five reasons to tune in
Get a jump-start on your CPHI Frankfurt experience with exclusive access to our online event platform.23 Aug 2022 -
News Artificial intelligence used to uncover ‘dark matter of the plant kingdom’
Brightseed uses its AI-enabled platform to detect natural bioactives important to human health, also known as ‘nature’s dark matter’2 Aug 2022 -
News WuXi STA launches new HPAPI production facility in China
The new plant features flow chemistry and milling technology, as well as reactors up to 3,000 liters1 Jul 2022
APIs (Active Pharmaceutical Ingredients) Products (2500+)
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Product Daptomycin RT
Daptomycin is a lipopeptide antibacterial agent active against gram-positive bacteria.
Indication: Used in the treatment of complicated skin and skin structure/soft-tissue infections caused by susceptible isolates of gram-positive bacteria such as Staphylococcus aureus&nbs... -
Product Parteck® SLC 500 EMPROVE® ESSENTIAL Ph Eur,NF
Parteck® SLC mesoporous silica is a multi-functional excipient for both solubility enhancement and particle engineering.
When used as a solubility enhancing excipient, the high surface area and small pores of Parteck® SLC mesoporous silica enable optimal stabilization of the more solubl... -
Product Parteck® MXP (Polyvinyl alcohol 4-88) EMPROVE® ESSENTIAL Ph Eur,ChP,JPE,USP
Poor solubility of APIs is a critical challenge in the drug development process. Our Parteck® MXP range of polymers includes two polyvinyl alcohol-based excipients, specifically designed and optimized for hot melt extrusion to increase solubility for a broad range of APIs.
q... -
Product Amphotericin B
Amphotericin B is a mixture of polyenes active against a wide variety of fungi e.g. Aspergillus, Candida and Cryptococcus species.
Indication: Used in the treatment of severe, invasive, potentially life-threatening fungal infections (mycosis) typically in immunocompromised patients. q... -
Product Hyaluronan/Hyaluronic Acid/Sodium Hyaluronate
Hyaluronan, is a biological polymer that is naturally present in the human body. It’s been used for decades in medical devices in an array of therapeutic fields including ophthalmology, rheumatology, aesthetic medicine. New fields for this highly effective API are continuing to ... -
Product Latanoprost
Filings: US-DMF, CEP*, C-DMF, K-DMF, T-DMF
*under preparation/submission
C2 PHARMA provides a wide range of active pharmaceutical ingredients (APls) and complex chemical compounds obtained from synthetic and natural which includes Latanoprost. It is used as a 0.005% ophthalmic solution for ... -
Product Bimatoprost
Filings: US-DMF, C-DMF*, K-DMF*, ASMF, Canadian-DMF*
*under preparation/submission
C2 PHARMA provides a wide range of active pharmaceutical ingredients (APls) and complex chemical compounds obtained from synthetic and natural origins which includes Bimatoprost. As 0.03% ophthalmic solution it... -
Product Bupropion Hydrochloride
Dipharma manufactures wide range of active pharmaceutical ingredients which includes Bupropion Hydrochloride. It belongs to commercial products category. Therapeutic category: Antidepressant. Contact us for more information. -
Product Fexofenadine Hydrochloride
Dipharma manufactures wide range of active pharmaceutical ingredients which includes Fexofenadine Hydrochloride. It belongs to commercial products category. Therapeutic category: Antihistaminic. Contact us for more information. -
Product Intermediates and API Plant to Lease or Purchase/Operate In Place
PRODUCTION AREA OVERVIEW
• (1) Reactors (SS, GL, Hastelloy): 3.4 – 16 m3 • (2) Centrifuges (Hastelloy): 1,600 mm diameter • (2) Conical Dryers(Hastelloy): 3 m3 Other process steps: Distillation, Filtration, Sieving & Milling
... -
Product Active Pharmaceutical Ingredients and Intermediates
We provide customized chemical synthesis for active pharmaceutical ingredients from concept to commercial supply.
We are an industry-leading integrated development and manufacturing service provider for small molecule drug substances and their intermediates.
Chemistry is c... -
Product API Pharmaceutical Plants and Equipment - Used Equipment and Complete Sites Available
IPP has available complete pharmaceutical plants that can be operated in place as well as relocation.
We have recently acquired pharmaceutical systems in both API and Formulation that can be moved to your plant site saving your projects 50-60% of the equipment value versus new. You can also save... -
Product CARBOWAX™ SENTRY™ Polyethylene Glycol (PEG)
CARBOWAX™ SENTRY™ PEGs common applications include: carrier/plasticizer in gel capsules, base for face/neck lotions, providing formulation stability in toothpaste, binder for tablets, shampoo wetting agent, and more. CARBOWAX™ SENTRY™ PEGs are available in average molecular weights ranging from 3... -
Product Processing aids – surfactants: TRITON X-100 & TERGITOL 15-S-9
Large Molecule (Biologic) API Production:
Dow’s TRITON™ and TERGITOL™ surfactants are used to inactivate virus envelopes, lyse cells, and buffer RNA extraction solutions. As the only producer of TRITON™ X-100 (CAS No: 9036-19-5), which has been trusted by the industry for deca... -
Product Active Pharmaceutical Ingredients
We cover the spectrum from clinical to commercial services to outsource active pharmaceutical ingredients (APIs), registered intermediates (RIs), and registered starting materials (RSMs). DSM services encompass most commercially-used chemical conversions. Some of our specialities include:
•Chiral te... -
Product Supply Chain Services
With a dedicated team of experienced supply chain specialists, we go far beyond conventional offerings to provide you with innovative and efficient supply chain solutions. With three strategically placed warehouses in Switzerland and Germany, we are able to store and distribute your products in a ... -
Product Active Pharmaceutical Ingredients
Actylis manufactures and supplies a wide range of active pharmaceutical ingredients (APIs) to many generic drug companies in the pharmaceutical industry. Active pharmaceutical ingredients are the active components of a drug product. Actylis is a valued partner in our clients' effort to develop and mar... -
Product HYALURONIC ACID
Hyaluronic acid, also known as Hyaluronan, is a biopolymer that is naturally present in the human body. It has been used for many years as a raw material or ingredient for medical products in various fields including ophthalmology, rheumatology medical aesthetics and dermatology.
HTL produces in... -
Product API & INTERMEDIATES
The CDMO Division of KD Pharma excels in the production of drug intermediates and API drug substances. We offer our customers the full spectrum of drug services: • R&D development material for preclinical studies • Pilot plant for phase I, II and III supplies • Large scale p... -
Product CordenPharma Peptides Platform
Your Expert Partner for Peptide APIs
• >> Proven track record delivering world class manufacturing services from early stage to commercial supply, including complex products (e.g., Linaclotide, Enfuvirtide, Mifamurtide, Eptifibatide, Glatiramer, GLP analogues). • >> Proprietary... -
Product Diazepam
FIS produces a wide range of API's which includes Diazepam. It is commercially available. Contact us for more information:[email protected] -
Product Diosmin
HTBA Diosmin is a flavonoid that is used as a venotonic for the chronic treatment of CVD, varicose veins, hemorrhoids, spider veins, and heavy legs syndrome. It is a GMP-certified API that promotes blood circulation and addresses vascular discomfort. It is produced through a solvent-free method and complie... -
Product Inhalation Product Analysis and Testing
Inhalation product analysis and testing services include particle size and droplet characterization, delivered dose testing, as well as aerodynamic particle size analysis – for pressurized metered-dose inhalers (PMDI), dry powder inhalers (DPI), nebulizers, and soft mist inhalers. Our Good Manufacturin... -
Product Sodium Hyaluronate Hyaluronsan HA-AM
Sodium Hyaluronate (API): MW 600 - 1,200 kDa Certificates: GMP certified sodium hyaluronate powder extracted from chicken comb, DMF in Japan, USA, China and South Korea
Application: Used in the pharmaceutical preparations for knee-osteoarthritis injection,... -
Product Rosuvastatin Tablets
Each film coated tablet containsRosuvastatin Calcium EP equivalent to Rosuvastatin 5/10/20/40 mg -
Product PVP-iodine Complex
PVP Iodine complex kills microorganisms on contact, is safer and easier to use than classic iodine preparations and has low systemic toxicity. In addition, it forms films that protect open wounds. Because it is soluble in water as well as in organic solvents, it an be formulated in powders, tablets, lozeng... -
Product Agomelatine
Agomelatine,阿戈美拉汀,C15H17NO2,cas#138112-76-2
Agomelatine is a melatonin receptor agonist and 5-HT2C receptor antagonist. Treat depression in adults.
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Product Acyclovir
Hetero Drugs Limited offers a wide range of active pharmaceutical ingredients for regulated market which includes acyclovir. Contact us for more information. -
Product Cloperastine Hydrochloride
Cloperastine is primarily a centrally acting cough suppressant used for non-productive cough. It also has some antihistaminic action. The hydrochloride has been given by mouth as tablets in usual doses of 10 to 20 mg three times daily. Cloperastine fendizoate is used in oral liquid preparations in equivale... -
Product Chemical Development
For the pharmaceutical, veterinary or cosmetic industry, our chemists have experience in route scouting and in developing scalable, innovative, sustainable, safe and robust processes up to GMP manufacturing for toxicological and clinical studies. We are also experienced at handling and manufacturing from t... -
Product Diosmin
Bordas diosmin is used to improve blood circulation in the veins by strengthening blood vessel walls and reducing inflammation. This can help relieve symptoms of venous conditions, such as swelling, pain and a feeling of heaviness in the legs.
It is a GMP-certified API and we have a CEP and DMF for Di... -
Product DIOSMIN/HESPERIDIN (90/10)
Diosmin/Hesperidin(90/10)
Micronized/Non-micronized
Documents:DMF
Diosmin WC
Hesperidin WC -
Product Thyroid
BIOFAC manufactures Thyroid USP from porcine thyroid gland according to USP with standardized content of both T3 and T4 hormones.
Thyroid USP is easily absorbed by human body and shown to have less side effects compared to synthetic drugs in the treatment of Hypothyroidism. -
Product Diosmin
Diosmin EP8.3 EP9 BP. 90%, 92%, 95%;
Diosmin/Hesperidin(90:10)
Particle Size: Non-micronized, Micronized, Granulated
EUGMP, CEP, Written Confirmation (EU), ISO, DMF
Annual Capacity 600 tons/ year -
Product Active Pharmaceutical Ingredients (APIs)
We provide the high quality active pharmaceutical ingredients globally. We are one of the leading manufacturers of active pharmaceutical ingredients in the world.
Balsalazide Disodium Dihydrate (US, TW, IN, KR)
Benzonatate (US, TW, IN, MX, CN, SG)
Calcipotriol Anhydrous ... -
Product Semaglutide API
Recombinant Semaglutide for Diabetes and Obesity. Available in oral grade with purity of >98% and injection grade with purity >99%. DMF available. Annual capacity of 300 Kg. By 2022, the global sales of Semaglutide preparations will be approximately USD 24.3 billion, in a high-growth phase, with huge... -
Product KSM & API Solutions
We supply high-quality Active Pharmaceutical Ingredients (APIs), adhering to cGMP standards. Our approach is innovative, starting with paperless labs for efficient R&D. Quality by Design principles guide our process design, ensuring safety and efficiency.
Our technology transfer ensures a se... -
Product Cannabis Extractum Normatum
Active Pharmaceutical IngredientDAB 2020 compliant
Substance origin: Cannabis Sativa L.
Certifications: Czech Medicines Agency (SUKL.cz), ISO 9001:2015, ISO 14001:2015 -
Product Beclomethasone Dipropionate
Axplora manufactures a wide range of commercial APIs which includes Beclomethasone Dipropionate.
Therapeutic area: Respiratory.
Grades: Anhydrous crystalline, Anhydrous micronized, Anhydrous sterile micronized, Monohydrate micronized.
Regulatory Documentation: CEP, EU DMF, US DMF... -
Product Acepromazine maleate [vet]
WELDING GmbH & Co. KG founded in 1955, independent, family-owned. Global marketing, sourcing and distribution of APIs for human and veterinary medicines, additives for the food and feed industry.
Development of finished products, including services related to IP evaluation, regulatory affairs ... -
Product Cortellis Generics Intelligence™
Never miss an opportunity using the most comprehensive intelligence available. Success in the highly competitive generics market requires speed and data-driven decisions to grow your business, defend your market share, stay ahead of competition and identify new markets, products and partners. Have confiden... -
Product SOMAÍ APIs
Extraction method: Cryo-ethanol extraction with decarboxylation / VTA distillation
Origin: Portugal, EU
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Product Paracetamol (Acetaminophen) 40,000Mt/Year
Annual Output Capacity: 40,000 tonsWide range In different particle size distribution
For human, animal and technical purpose
China GMP/CEP/EU GMP/US FDA/DMF available
EHS compliance with ECOVADIS/PSCI Certification
HALAL Certification
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Product lenacapavir
It is a type of anti-HIV medication that can treat patients with multi-drug resistant HIV. It has a multi-stage mechanism of action that is different from other antiviral drugs; it can inhibit multiple stages of the HIV life cycle simultaneously and has no known cross-resistance. -
Product Dipiperon® (pipamperon)
Eumedica pharmaceuticals offers a wide range of products which includes dipiperon® (pipamperon). Contact us for more information.
Dipiperon® (pipamperon) is a prescription drug in psychiatry. -
Product Flurbiprofen,
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. -
Product CTP, 100mM Sodium Solution
CAS No. 123334-07-6Molecular Weight: 549.10
Molecular Formula: C9H13N3Na3O14P3
Storage: -20℃
Purity≥99%(HPLC)
Specifications: 1mL、10mL、100mL、500mL -
Product Glycerophosphocholine (GPC)
VAV Lipids specializes in the production of cGMP Phospholipids & Lecithins from Natural sources (Soybean, Sunflower, Egg) and Synthetic Lipids. VAV also produces other Specialty Lipids like Glycerophosphocholine (GPC), Cholesterol as well as Phospholipid based Delivery Systems. Our products find appli... -
Product APETAMIN
Til healthcare pvt ltd provides wide range of appetite stimulant which includes apetamin. Feature: cyproheptadine + multivitamin + lysine. Dose: 2 mg. Dosage form: syrup. Shelf life: 18. Packaging: 120 & 200 ml. Contact us for more informations. -
Product Urokinase
1、A kind of zymoprotein extracted from human urine
2、Activate the endogenous fibrinolysis system and convert plasminogen into plasmin
3、Favorable ...
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Product Directly Compressible Granules
1. Aceclofenac Granules 50%2. Clopidogrel Granules 60%
3. Fexofenadine Granules 48%
4. Gliclazide Granules SR 48%
5. Levitiracetam Granules SR 75%, 80%
6. Lisinopril Granules 50%
7. Metformin HCL Granules IR 86.66%, 93%
8. Metformin HCL Granules SR 75%, 80%
9. Montelukast Granules 7.1%... -
Product Vitamin D2
Sichuan province yuxin pharmaceutical co. Ltd offers a wide range of products which includes ergocalciferol. It is white crystal powder,smellless,tasteless. Packing: inner packing: aluminium bag, outer packing :aluminium tin. Contact us for more information. -
Product Nintedanib API/Tab
Used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer -
Product FOAM CONTROL SOLUTIONS FOR FERMENTATION PROCESSES
Consolidated range of antifoams for fermentation processes, providing excellent durability and foam control performance.
We offer antifoam solutions that are proved to be stable under sterilization and autoclavable, Halal & Kosher certified.
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Product Urea with DMF and GMP
Fischer Chemicals AG offers a wide range of active pharmaceutical ingredients. Contact us for more information. -
Product Copovidone VA64/ PVP VA64
Copovidone is a water-soluble polymer resin, white powder, odorless and tasteless, easy to absorb moisture, soluble in water, ethanol and anhydrous alcohols, with good cohesiveness, hygroscopicity, film-forming properties and surface activity.The main application is as follows,
(1)Pharmaceutical field: ... -
Product Aprotinin
Aprotinin is a single chain polypeptide of 58 amino-acid residues. It is also known as basic pancreatic trypsin inhibitor (BPTI) or as trypsin-kallikrein inhibitor.
Pentapharm produced this active pharmaceutical ingredient grade quality Aprotinin which can also be used in the following application... -
Product Sunvidone ® PI Solution
SUNVIDONE PIS is a deep-brown solution of Sunvidone PI in water. They are stablebroad spectrum and non-selective germicidal antiseptics and disinfectant which havedetoxified iodine, no general odor, no loss of iodine, no detectable vapor pressure. They arewater soluble, Film-forming and effective in dilute... -
Product Recombinant Insulin
Recombinant Insulin (also known as Insulin Human AF) is a recombinant protein, consisting of human insulin crystals, a biosynthetic product expressed by recombinant microbial expression in yeast.
As insulin binds to its receptor, it initiates different intracellular signaling pathways involved... -
Product Diosmin
Diosmin is a capillary protective drug, which is used to treat various symptoms related to venous and lymphatic insufficiency, such as venous edema, numbness and heavy limbs, and treat various symptoms of acute hemorrhoid attacks, such as itching, blood in the stool, pain, etc. -
Product API Services, Chemical Development & Manufacture
Almac’s strength in API development and manufacture is proven by being the partner of choice for many pharma and biotech companies seeking integrated drug development solutions from molecule to market.
Our technical expertise and extensive facilities enable us to offer integrated API contract ma... -
Product Omeprazole Sodium
It is a drug mainly used for: ① peptic ulcer bleeding, anastomotic ulcer bleeding. ② Acute gastric mucosal damage complicated by stress state and acute gastric mucosal damage caused by non-steroidal anti-inflammatory drugs; ③ It is also commonly used to prevent severe diseases (such as cerebral hemorrhage,... -
Product Quadrivalent Subunit Influenza Vaccine
As the latest generation of influenza vaccines produced in China,Ab&B Bio-Tech CO.,LTD.JS Hui'erkangxin contains four types of influenza viruses: H1N1 A-type, H3N2 A-type, B-type BV, and B-type BY.This vaccine adopts a safer subunit process, milder extraction agents, and more efficient injectors. ... -
Product Active pharmaceutical ingredients services
Taking advantage of our global presence with offices located in all the key areas for the chemical and pharmaceutical business, Summit Pharmaceuticals Europe can provide a large range of different APIs.
Due to our long experience and consolidated relationships with our partners we can provide material f... -
Product PGMs sponge
PGMs foils, bars or sponges have a purity of at least 99.95% and they are available in the format ordered and chosen by the client.
Delivery of metals is carried out by the most trustworthy courier services which are fast and equipped to transport valuables, both in Italy and all around the world... -
Product 2023-Product Types
Product types covered by TPA members-Download our brochure or Contact [email protected] for more information -
Product Heparin Sodium; Enoxaparin Sodium
Source: Extracted from pig intestinal mucosa;Heparin Sodium:Function and use: It is an anticoagulant. It affects many aspects of the coagulation process and can prolong the coagulation time and prothrombin time. This product has rapid anticoagulant effect both in vivo and in vitro. It mainly acts on the fo... -
Product Indapamide
Gaohua pharmaceuticals Co., Ltd. is the leading manufacturer of Indapamide and clastine famurate API and drugs. We have factories in Shan’xi and Jiangxi province as well,which produce Chinese Patent medicine and other drugs such as: Amoxicillin capsules, Norfloxacin capsules,vitamin, Acetaminophen tabl... -
Product RoSS®: Protecting single-use bags
Protect your preferred single-use bioprocess containers: RoSS shells - abbreviated for Robust Storage and Shipping - reduce product loss towards 0%. Compatible with all available sizes and types of single-use bags, RoSS enables standardized and scalable end-to-end process solutions for fluid managemen... -
Product TURBULA®
Container volume of 0.1 to 55 liters.
The TURBULA® mixer is used for homogeneous mixing of powdery substances with different specific weights and particle sizes. Producing dry-to-wet and wet-to-wet mixtures is also possible.
The production process is hygienic and dust-free because the product is ... -
Product HCl CPME / HCl 1,4-Dioxane / HCl IPA / HCl EtOH / HCl MeOH / HCl BuOH
Hydrogen chloride (gas) dissolved in organic solvents at tailor-made concentrations ready to be used in your API and Fine Chemicals synthesis process.
These mixtures will bring less risks (i.e no hazardous gas handling), more productivity (i.e free up space in the reactors) and increased flexibility... -
Product Montmorillonite(Dioctahedral Smectite)
Dioctahedral smectite of pharmaceutical grade is a great product that our company select from high quality bentonite, and adopts advanced technology to manufacture, and use the advanced craft, refined it after purify highly according to the medicine standard.
Mechanism of Action:
Ø ... -
Product AIRFREIGHT WITH GDP ACTIVE AND PASSIVE COLD SOLUTIONS
As IATA cargo agents, and GDP certified we offer direct services with the main airlines allowing us to offer the best air cargo, EXPORT and IMPORT and Cross-Trade rates, providing end-to-end logistics solutions from/to anywhere in the world.
We have air consolidation services and Chartering services. ... -
Product Phenylbutazone
There are CEP certificate and US VMF, approved by FDA for more than three years. Our main markets are European and US.
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Product Pravastatin Sodium
• Specification: USP, EP, JP, ChP • Production Capacity: 40 tons/year • China NMPA, US FDA, Korean MFDS, PMDA approved • CEP • WC • COPP
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Product Albumin Tannate
Albumin Tannate is an API with GMP certification specially indicated for anti-diahrrea proceses. Its astringents properties helps to not loose water and cut diahrrea. DMF open and close part available for Europe, America and Asean, China in progress.
It is a light brown to brown, amorphous and hygroscop... -
Product Single use powder transfer bag
Flexible bag ,offer good ergonomics deign, and easy to manipu.Antistatic film which reduce powder loss and explos.High containment to protect the operator, eliminate potential safety risk and avoid the contamination of the work environment during handling, transfer or transport of the fine powder.3-100L ... -
Product Metamizole Sodium-Antipyretic Analgesic
Metamizole Sodium is white or almost white crystalline powder. Very soluble in water, slightly soluble in ethanol (96 percent), practically insoluble in methylene chlorideone. -
Product Fluorometholone Series
Fluorometholone is the topical synthetic glucocorticoid. Its tropical anti-inflammatory effect is 40 times as much as hydrocortisone, but their effects of oral administration are almost equal. It is mainly used for local treatment of skin allergy, pruritus, rash and other diseases related to allergy. Oral ... -
Product semaglutide
we can supply the semaglutide API with a good price and good quality,we are also open for the cooperation model. -
Product Omega-3 API
Kinomega Biopharm Inc provides omega-3 fatty acids EPA/DHA which includes omega-3 API. Our master formula: KinOmega 4638EE, Omega-3 Acid Ethyl Ester 90%, EPA 430mg/g min.+ DHA 347mg/g min., EPA+DHA 800mg/g min., KinOmega E97EE, and Icosapent Ethyl 96.5%. Contact us for more informa... -
Product Hydrotalcite
A drug to neutralize stomach acid.For the treatment of stomach and duodenal ulcers or gastric acid caused by excessive acid return, heartburn, pain, abdominal distention, belching and other symptoms.CAS NO. 12304-65-3,
Standard: BP/CP. -
Product Venetoclax
We offer an integral secure solution as your startegic partner of Venetoclax.
Venetoclax (CAS 1257044-40-8) is a targeted therapy drug used to treat chronic lymphocytic leukaemia (CLL), manufactured in our unique European GMP manufacturing plant located in Barcel... -
Product Chlortetracycline HCL
Packing: 25Kgs/Drum or carton
Certifications: Chinese GMP, U.S.FDA, EU-GMP, COS, MAFF approval
Product Advantages:
●Uniquely approved for human use grade
●Fine solubility
●Fine color
●High Biological Assay
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Product Drug Substances
With more than 30 years of experience in Pharma, Midas has demonstrated a proven track record & expertise in sourcing and supplying Drug Substances (APIs) required for the pharmaceutical production. We work closely with our manufacturing partners around the globe and are active in more than 700 dr... -
Product Erythropoietin Alpha
Indication: Chronic kidney diseases induced anemia (dialysis and non-dialysis)
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Product RIFAXIMIN
Rifaximin: Red-orange crystalline powder, an antibiotic used to treat traveler's diarrhea, irritable bowel syndrome and hepatic encephalopathy. -
Product Polyglykol
Effective and high-purity ingredients including a complete range of Polyglykols (Macrogols) our universally applicable pharmaceutical polymers, with various molecular weights, supported by CEP certification and DMF type II documentation. -
Product UPO Enzyme Screening Kit
- 77 fungal unspecific peroxygenases (UPOs)
- Rapid hit screening with the panel
- Free of third party IP
- UPO supply up to kg scale
Revolutionize your API synthesis route by using biocatalysis to oxyfunctionalize your substrate!
We offer the largest c... -
Product Sodium Hyaluronate - Injection grade
Hyature® is a pharmaceutical grade sodium hyaluronate which can be used as an API or excipient for drugs and medical devices in ophthalmic preparations, intra-articular injections, anti-adhesive preparations, topical preparations for wound healing and soft tissue filler, etc. Hyature® sodium hyalur... -
Product 1-Boc-3-azetidinone
Shanghai Jinli Pharmaceutical is the leading barticinib intermediates manufacturer, the Tert-butyl3-oxoazetidine-1-carboxylate CAS # 398489-26-4 is our strong product. -
Product 2,3,4-Trihydroxybenzaldehyde
Name: 2,3,4-Trihydroxybenzaldehyde
CAS No: 2144-08-03
EINECS No.:218-404-2
Chemical Name: Pyrogallolaldehyde
Structure Formula:
Molecular formula&Molecular Weight: C7H6O4; 154.1201
App... -
Product Small Molecules
Our multi-patented Controlled Expansion of Supercritical Solutions (CESS®) technology enables the creation of API nanoparticles directly from solution. The process can be applied to most small molecules, with a high success rate of 80-90%.
CESS® is a bottom-up method of recrystallization that wo... -
Product D-Mannose
D-Mannose is solid at room temperature, with an off-white to yellow crystal appearance. It is odorless, and the taste is both sweet and bitter. D-Mannose can support and promote a healthy bladder and urinary system.
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Product Paracetamol
SEQENS offers wide range of products which includes paracetamol. Contact us for more information. -
Product Mediprene Mass Balance TPE
Mediprene Mass Balance Thermoplastic Elastomers are medical TPE materials with bio-attributed content according to the mass balance principle.
They were developed to enable the shift away from fossil resources and support the reduction of greenhouse gas emissions, while ensur... -
Product Pygeum Bark Soft Extract
Specifications2.5% & 13% Phyto-Sitosterols by HPLC
Application Urologic, Prostate Support
Botanical Source Prunus Africana -
Product Elimreal
ELIMREAL® is a new patented exclusive natural and powerful elimination complex that stimulates natural body drain functions and body detoxification. ELIMREAL® efficiency has been demonstrated clinically during double-blind against placebo studies, increasing Urinary Volume and Frequency. Approved worldwide... -
Product Combination Products
A combination product is the combination of a physical part and a drug which can be implanted or worn on the body for long-term treatments. Combination products offer several advantages when compared with drug delivery via oral, injection, and infusion methods:
Controlled release of the Ac... -
Product Articaine or carticaine
Moehs Fine Chemicals provides a wide range of generics which includes articaine or carticaine under GMP guidelines. FDA approved site. It belongs to local anesthetic- antiarrhythmic category. Packaging: Fiber drum 50 Kg. CEP, EDMF, USDMF available Contact us for more information... -
Product Varsaltan
Valsartan is one of our mature products, with an annual production capacity of 240mt/year. With the strong strength of China Resources Double-Crane Pharmaceutical Co., Ltd., our company has continuously improved and optimized production, R & D, technology and equipments to ensure that the product quali... -
Product APIs
• Paclitaxel (Package : Up to 500g Per request) • Pemetrexed (Package : Up to 1kg Per request) • Bortezomib (Package : Up to 40g Per request) -
Product Heparin Lithium
It is an anticoagulant commonly used in chemistry and specially chemistry testing and routine clinical chemistry determination. It is the recommended anticoagulant for many determinations using whole blood or plasma specimens because of its minimal chelating properties, minimal effects on water shifts,... -
Product PHARCOCEL - HPMC / Hypromellose / Hydroxy Propyl Methyl Cellulose
Pharmaceutical grades of HPMC will have detailed specification as per specific monograph. All our HPMC grades will be available in powder & granular form. -
Product FENOFIBRATE, DEFERASIROX, BENFOTIAMINE, ITOPRIDE, SITAGLIPTIN
HYPERCHOLESTEROLEMIA, ORAL IRON CHELATOR, -
Product Suitable Supports
Offering Tailor-made catalysts for optimum productivity in your process.
Hindustan Platinum is a leading manufacturer of precious metal catalysts that play a pivotal role in chemical industries, owing to their activity, selectivity and recyclability. Our catalysts are abundantly suppli... -
Product 5 HTP
L-5-HYDROXYTRYPTOPHAN: NLT 99.0%
PHARMA USE
InsomniaPost-anoxic myoclonus
Anxiety and depression
Migraines
DIETARY USE
Sleep improvement
Promotion of positive moods and emotions
Appetite control and adherence to slimming programs -
Product HPAPI Platform
Responding to the rising number of custom HPAPIs demand, Angelini Fine Chemicals expands its HPAPI capacity. With over 50 years of CDMO experience, Angelini Fine Chemicals is at the forefront of chemical development and cGMP manufacturing of HPAPIs to serving brand pharmaceutica industry. The new Angel... -
Product APISAL (Sodium chloride API)
For the exceptionally high requirements in pharmaceutical manufacturing processes, we produce pure pharmaceutical salt exceeding the purity requirements stipulated in the pharmacopoeias. All steps of production, analysis, and quality control comply with these strict principles. APISAL® is obtained from a p... -
Product VORICONAZOLE
Voriconazole is used to treat serious fungal or yeast infections, such as aspergillosis (fungal infection in the lungs), candidemia (fungal infection in the blood), esophageal candidiasis (candida esophagitis), or other fungal infections (infections in the skin, stomach, kidney, bladder, or wounds) -
Product Lansoprazole
INTEGRIN LIFE SCIENCES PVT. LTD. offers wide range APIs and Intermediates which includes Lansoprazole. Contact us for more information. -
Product XanGuard® Lutein and Zeaxanthin
Lutein and Zeaxanthin are the main pigments in the macular area of the retina and play important role in eye health. They can be found in green cauliflower, spinach, egg yolk and other foods, extracted from marigold is the first choice for industrial production.
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Product Amphotericin B
It is used to treat severe visceral or systemic infections caused by deep fungi -
Product Primary API reference standards
Mikromol reference standards for Active Pharmaceutical Ingredients (APIs) are primary quantitative standards – the majority accredited to ISO 17034 and designed to ensure the highest analytical accuracy and reliability. Their intended use is for potency assessments, drug substance and drug product release ... -
Product Glimepiride
PHARMACOPOEIA : IP/EP/USP/JP | THERAPEUTIC USE : Anti-Diabetic | DMF : Available -
Product FERRIC CITRATE
Greenish brown to brown hygroscopic powder. Powder & DC grade available. DMF & Patent available -
Product Polysorbate 80 / Hedisan-80 (API)
Hedisan-80 is a high quality Polysorbate 80. The product is produced at Kolb in Hedingen. The site has been authorised by SwissMedic to manufacture and distribute active pharmaceutical ingredients and is subject to regular GMP inspections. Kolb has a broad portfolio of non-ionic surfactants with... -
Product Z-Arg(Pmc)-OH.CHA CAS:112160-33-5
We are very compeitive on Z-Arg(Pmc)-OH.CHA CAS:112160-33-5 with high quality on commercial scale
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Product Drug Substance
Recipharm has more than 25 years’ experience in drug substance development and manufacturing. We are ideally placed to deliver a wide range of drug substance services from our dedicated development facilities around the world. -
Product CDMO Services
Strong R&D with over 100 patents filled and 4 cGMP manufacturing sites offering from pre-clinical to commercial supplies (from grams to multi-tons).
With available capacity to start supporting your project now! -
Product Alzepizil
For dementia and Alzheimer
Global Napi Pharmaceuticals offers a wide range of products which includes alzepizil. Alzepizil tablet contains donepezil HCl as 5 mg or 10 mg donepezil base. Use: Alzepizil is used for treatment of mild-to-moderate dementia of the Alzheimer's type. Contact us ... -
Product Cabergoline IP/USP/EP
Global calcium manufactures wide range of pharmaceutical products which includes anhydrous magnesium citrate bp. It belongs to magnesium products category. It is a white or almost white, fine, slightly hygroscopic powder. It is soluble in water, practically insoluble in ethanol (96 %). It dissolves in dil.... -
Product Pactol Cough Adults
MASENZ DANYA GROUP SL offers a wide range of products which includes pactol antitussif (adult). Contact us for more information. -
Product Calcium Polystyrene Sulphonate (Doshion P 548)
DOSHION P548 is an Active Pharmaceutical Ingredient in bulk complying with the British and Japanese Pharmacopeia where it is listed as 'Calcium Polystyrene Sulphonate'. Chemically, it is a non-solvent, powdered, strong acid cation exchange resin in calcium form. Calcium Polystyrene Sulphonate is norma... -
Product Sodium Hyaluronate (Hyaluronic Acid API): MW 250-2300 kDa
Sodium Hyaluronate (Hyaluronan, HA) - TYPE I: MW 250 - 2300 kDa
Ultra-Pure HA
Pharmaceutical Grade (Injection suitable)Certificates: GMP, CEP, DMF
Our Intrinsic Viscosity is from IV 0.7 to 2.8 m3/Kg
Sodium hyaluronate is a polysaccharide found... -
Product Diphenyacetic Acid
Diphenylacetic acid is a monocarboxylic acid that is acetic acid where the methyl hydrogens have been replaced by two phenyl groups respectively. It has a role as a xenobiotic metabolite.
Shree Ganesh Remedies Limited is one of the leading manufacturer and supplier of the Diphenyaceti... -
Product Algal DHA
Algal DHA, a vegetarian, sustainable and highly stable algal Omega-3 DHA produced from the microalgae Schizochytrium. Although fish oil is well known for having a high content of EPA and DHA, micro algae is the original source of marine omega-3. Algal DHA is the DHA in Algal oil that is derived directly fr... -
Product SÜDZUCKER COMPRI® M3000
Südzucker COMPRI® M3000 is an agglomerated, directly compressible sugar with parts of maltodextrin. It is suitable e.g. for the production of confectionery or pharmaceutical tablets.
PRODUCT BENEFITS
· Di... -
Product PHSE UK
• Specialty courier dedicated to clinical trials and the drug development process • Import and export from more than 70 countries including 3rd country and direct to site 24hr operations 7 days per week, 365 days per year • Walk in cold chain facilities for high volume supply of temperature contro... -
Product Diminazene Aceturate
NGL Fine-Chem Ltd manufacturers wide range of pharmaceutical products which includes Diminazene Aceturate. It belongs to API's animal health products category. It is a lemon yellow powder, odorless. Therapeutic Category : Antiprotozoal Contact us for more information. -
Product inline mixer CMX with 2 dispersing stages
The IKA CMX 2000 is an inline mixer for rapid and homogeneous incorporation of powders into liquids. The circulation of fluid creates a powerful vacuum in the machine that draws in the powder. This ensures an agglomerate free integration of problematic powders that are not easily incorporated into the liqu... -
Product Highly Potent API
CARBOGEN AMCIS has state of the art facilities and controls to handle both drug substance and drug product of the highest potency and toxicity, under cGMP. Our dedicated containment facilities use a containment methodology, utilizing barrier isolation technology and Rapid Transfer Ports (RTPs), combined wi... -
Product Manufacturing
Custom API Manufacturing, Fermentation, Finished Dosage Form, High Potency, Lipid Nanoparticle, Rare / Orphan, Stability & Release Testing, Sterile Fill Finish, APIs & Intermediates, Fine Chemicals
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Product Custom API
AbbVie’s API site has the flexibility to run multiple chemical processes simultaneously to support late development phase to commercial products including highly potent drug containment up to OEL 3A (1 µg/m3). State of the art QC laboratories integrated across a highly experienced team focused on commercia... -
Product Active Pharmaceutical Ingredients
OLON is an Italian company world leader in the Active Pharmaceutical Ingredients (APIs) production, using synthetic and biological processes for Generic market as well as in Contract Development and Manufacturing (CDMO).
Always considering human safety and environmental security, OLON hand... -
Product Gaskets for pharmaceutical applications
Dockweiler gaskets ensure the availability of various materials from approved high quality vendors to complete our high quality product range of tubular components. Dockweiler guarantees total traceabilty even for gaskets: laser engraved, lipped gaskets with material certification. Dockweiler gaskets are c... -
Product Early Phase Support
From the lab to the plant:• Development of new, scalable API route options
• Process safety and hazards assessment
• cGMP starting material assessment& establishment of regulatory concept
• Starting material & other raw materials sourcing and development
• Polymorph screening & salt... -
Product Clarithromycin Taste Masked Coated Granules
White to off white tasteless free flowing granules.Recomended for Dry Syrup / Suspension
Available activities 27.5%, 30%, 33%, 38%, 42%, & 43.75% -
Product Chlorthalidone
CAS Number: 77-36-1
Formula: C14H11ClN2O4S
Molecular Weight: 338.8
API
Aplication: Diuretic - Hypertension treatment
DMF, CEP, KFDA, GMP, USDMF
www.menadiona.com
[email protected] -
Product CDMO services for APIs
With more than 50 years experience, Novasep offers a full range of CDMO services for APIs, from clinical supply to commercial scale manufacturing:
Process development services
• Technical transfer • Process development & scale-up • Development, optimiza... -
Product Pre-formulation development
WuXi STA's IND Enabling Preformulation Package (IEPP) is an integrated end-to-end developability assessment service for new chemical entities (NCE). Efficiently identify challenges and solutions earlier for higher success rates and lower overall costs. PK formulation, Profiling, Form selection, and&nb... -
Product NORMOBOWELL
Medical Device for the management of Irritable Bowel Syndrome.
MEDICAL DEVICE CE 0477 CLASS IIB -
Product Clavulanate Potassium with Microcrystalline Cellulose (1:1)
Clavulanate Potassium with Microcrystalline Cellulose (1:1)
Production capacity: 900 tons
Quality standard: USP (%~%); EP (91.2%~107.1%)
Certificate: USDMF 25719
CEP2011-375
Chemical N... -
Product Triptorelin Acetate
Product Name:Triptorelin Acetate;Cas No. 57773-63-4;Sequence Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2;Molecular Formula C64H82N18O13;Molar Mass 1311.5 g/mol;Purity ≥98%;Impurity ≤0.5% ;Storage Temperature 2-8℃;Packing Size 1G/Bottle, 10G/Bottle,50G/Bottle or at customers reqirement.
Triptorelin Ace... -
Product Antazoline Hydrochloride
Fields of Application: Conjunctivitis. Antazoline Hydrochloride is an ethylenediamine derivative with antihistaminic properties and is used in conjunction with a vasoconstrictor for ocular allergies. -
Product Optiserum sterile eye wash 5ml single dose 10
Laboratoires Gilbert provides wide range of health products which includes optiserum sterile eye wash 5ml single dose 12. Brand name: physiodose and a-earwax. It is a sterile solution in single-dose, perfectly suited to the eye hygiene. Its composition ensures identical to that of tears ph. The cornflower ... -
Product API PORTFOLIO
Hovione's APIs offer impeccable chemical purity and unique product performance.
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Product Pharmacopea Analysis
Neotron SpA provides wide range of analytical control according to EP, USP, JP, BP, CHP.
Contact us to ask for tests in relation to your monograph of interest. -
Product Oxacillin sodium
Reyoung Pharmaceutical Co. Ltd. is one of the leading manufacturer and distributor of pharmaceutical products.
It has 31 workshops, which can produce ten categories and more than 400 specifications of pharmaceutical products including tablets, capsules, granules,... -
Product (Z)-3-Iodopropenoic acid methyl ester
Synonyms : (Z)-3-Iodopropenoic acid methyl ester; Methyl (2Z)-3-iodoprop-2-enoate; 3-Iodopropenoic acid methyl ester;Chemical Formula : C4H5IO2
Molecular Weight : 211.9858
Appearance: Yellow to red Clear viscous oil.
Moisture : Not more than 0.50%
Gravity (at 25 °C ) : 1.90 to 1.92 gm /ml
Bo... -
Product Ginkobil 60,80,120 Mg Hard Capsules
BLOOD FLOW TREATMENTGinkgo extract (Ginkgo biloba) 60 mg / 80 mg / 120 mg | hard capsules
Ginkgo extract and its active ingredients significantly improve cerebral and peripheral blood flow, brain cell condition, lower blood viscosity and improve memory.
Ginkobil is made from refined and q... -
Product Contract Manufacturing Solutions
GVK BIO offers long term Contract Manufacturing Solutions in development, validations, DMF filing, manufacturing of New Chemical Entities (NCE), Active Pharmaceutical Ingredients (API) and Intermediates.
Capabilities:Environment friendly routes under GMP conditions
Robust and cost-effective p... -
Product Nitrosamine Impurities Testing
SGS Life Sciences has considerable expertise in the method development of nitrosamine determination in pharmaceutical products. SGS has established a specific method for NDMA which can be applied to various different matrices. Alternatively, a platform method, based on trace-level detection by LC-MSMS, is ... -
Product Butorphanol Tartrate
Butorphanol Tartate is a morphinan-type synthetic opioid analgesic.
It is approved by NMPA. -
Product Mexiletine hydrochloride
Active Pharmaceutical Ingredient. Arrhythmia indication. Cardiovascular therapeutic area. -
Product POVIDONE, MICROCRYSTALLINE CELLULOSE, HYPROMELLOSE, CROSPOVIDONE, COPOVIDONE, CCS, COLLOIDAL MCC, LACTOSE, STARCH, SUCRALOSE, SACCHARIN, CYCLODEXTRINS, POLOXAMER, POLYSORBATE, PEG, API, INTERMEDIATES, FILTER BAGS, SILICA, SILICONES,
DILUENTS, BINDERS, DISINTEGRANTS, FILM FORMERS, PLASTICIZER, POLYMERS, SWEETENERS, SURFACTANTS, PEPTIDES, OMEGA 3 FATTY ACID, VITAMINS, DIETARY FIBRES, COCOA POWDER, ANTI AGEING, ANTI WRINKLES, MOISTURIZERS, ENCAPSULATED BEADS, SCRUBING BEADS, -
Product Sterile Process Manufacturing Vessel
Design as per ASME / APM Standard
All Contact part SS 316 L Quality and Non Contact Part SS 304 Quality
Provision for CIP/SIP Facility
Zero dead leg Flush Bottom Discharge valve with SIP Able.
Load cell Facility available
Ph Sensor / Conductivity Sensor / DO Sensor provide on Demand for Onli... -
Product Thermo Compression distillation system/ Vapour Compression distillation system
Thermo Compression distillation system is the most economical method of producing highest quality WFI. The system is available in wide range of production capacities, from 100 LPH to 5000 LPH. The system is fully automated, in compliance with GAMP5 standards and is also available to comply with 21... -
Product Clopidogrel Hydrogen Sulphate form 1 & form 2
The active substance Clopidorgel is an inhibitor of platelet aggregation. This means that it helps to prevent blood clots from forming. ... Clopidogrel stops the platelets aggregating by blocking a substance called ADP from attaching to a special receptor on their surface. Clopidogrel common... -
Product Cannabidiol (CBD)
Our product is an API-grade CBD purified naturally from the Hemp Plant. Cannabidiol (CBD) is a phytocannabinoid, a non-psychoactive molecule present in the Cannabaceae family of plants. CBD has been demonstrated as an effective treatment of epilepsy in several clinical trials. There is also preliminar... -
Product HRS Hot Water Systems
HRS Hot Water System is the most versatile and compact solution offered by HRS Process Systems Ltd. for hot water generation. It generates instantaneous hot water using energy efficient heat exchangers like HRS Funke Brazed or Gasketed plate heat exchanger or Ecoflux* corrugated tube heat exc... -
Product Fomepizole
An orphan drug API used in its finished form (injectable) is the only known antidote for methanol and ethylene glycol poisoning in the world. Available for all global markets along with DMF support.
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Product Dexbrompheniramine Maleate
Antihistamine API for treatment of cough cold and allergies. Phamacoepia USP -
Product Chondroitin Sulfate Sodium
Sichuan deebio pharmaceutical co. Ltd offers a wide range of product which includes chondroitin sulfate sodium. It belongs to polysaccharides category. It is a white or off white powder, slightly salty, odourless, hygroscopic. The water solution is sticky, and would not coagulate when heating. Soluble in w...
What are Active Pharmaceutical Ingredients (API)?
Drugs are composed of two major components: – Active pharmaceutical ingredient (API), and excipients. APIs vary from drug to drug and are responsible for creating the intended biological, physiological or therapeutic effect within the recipient's (patient's) body. A drug can contain one or more APIs depending on its purpose and the synergistic actions of the APIs.
Active pharmaceutical ingredients (APIs) are the therapeutically active substances or chemical components of drug products (capsules, tablets, syrups, etc.) that produce an intended pharmacological effect.
The APIs within drugs are conveyed into the body through inactive components known as excipients, which usually make up the bulk of the drug. They facilitate the ingestion, absorption, and distribution of the active ingredients. These excipients serve as vehicles and are usually inert or biologically inactive.
Source APIs from our marketplace of 900+ global API manufacturers and 2,500+ API solutions in categories such as Amino Acids, Enzymes, Antibiotics, Antibodies, Sera and Vaccines and more.
What is the purpose of APIs?
APIs are the primary ingredients contained in drugs and medicines. They play a significant role in drug production and produce pharmacological effects within the body. The pharmacological effects produced, directly or indirectly, influence the diagnosis, symptom relief, mitigation, treatment, cure, or prevention of diseases. APIs also modify, correct, or enhance the physiological function and structure of chemicals, cells, tissues, and organs within the body. In simple terms, they make the drug or medicine work.
What is the overall size of the API market?
With the exponential rise in the global population, the growing demand for a therapeutic solution to critical and chronic diseases, change of lifestyle, and the increasing importance of generics globally, the need for active pharmaceutical ingredients has skyrocketed. As a result of these, the API market growth is increasing at a rapid rate.
Based on research, the global active pharmaceutical ingredient market had an estimated value of $168.87 billion in 2019 and is presently worth $ 187.3 billion. However, the global market is expected to grow by the US $ 100 – 120 billion dollars in the next seven years to attain a market value of US $285.5 billion by 2027. The growth of the API market is expected to move at a CAGR of 6.8% during the forecast period.
This research covers growth trends and competitions in significant regions where APIs are actively manufactured and distributed. These regions include Europe, North America, Latin America, Middle and East America (MEA), and Asian Pacific (APAC). Although the majority of API manufacturing companies are located in the United States, others are located in India and China.
How APIs are synthesized?
API synthesis is a complex multi-step process that involves a wide range of chemical processes and reactions of varieties of raw materials by physical and chemical means. Specialized professionals in API manufacturing companies perform the process of active pharmaceutical ingredient synthesis and manufacturing.
APIs can be synthesized through 3 major processes – Biological process, organic chemical synthesis, and extraction from a biological source. The method used depends on the raw material involved, steps of the process, and complexity of the API molecule.
What steps are involved in the synthesis of APIs?
APIs are tiny complex molecules produced through a variety of processes. The complexity of the active pharmaceutical ingredient to be synthesized plays a significant role in determining the process used and the steps involved in the process. The steps involved in each of the three processes vary. Synthesis of APIs through biological processes include inoculum and seed preparation, fermentation, and product recovery.
Organic chemical synthesis of APIs involves the use of organic and inorganic chemicals and reactors to produce APIs. This process usually consists of the production of intermediates during chemical reactions. In some cases, these intermediates can be used to produce different APIs or used as a separate pharmaceutical entity. Extraction of APIs from a biological source involves passing natural materials through batch processes to extract or produce a pharmacologically active substance.
Although the stages involved in the various processes differ, they are all grouped into different stages - the introduction of raw materials, production of intermediates, isolation, and purification, and physical processing and packaging.
Given that technology is continually evolving, continuous flow-system has been introduced to enhance the API synthesis and manufacturing process.
How long does it take to synthesize APIs?
The length of the manufacturing process is majorly dependent on the complexity of the API molecule to be synthesized and the process used. API synthesis is a long and complicated process that may take months and sometimes, up to years to complete. The complexity of the structure influences the API synthesis period length, the number of steps in the synthesis route, type of synthesis, cost of the process, drug impurities present, number of APIs to be produced, and the number of isolation steps involved.
What is the goal behind the synthesis of APIs?
API synthesis facilitates the processing and manufacturing of pure pharmaceutical preparations (APIs) for clinical use. Through API synthesis, these active ingredients are extracted, purified, and packaged for treatment, diagnosis, cure, mitigation, and prevention of diseases. These APIs are synthesized and manufactured into biologically secure forms and substances to produce specific pharmacological effects within the recipient's body. Simply put, the primary goal of API synthesis is to create pure, potent, and safe APIs for drug development and production and administration to patients.
Challenges with API reactions and drug interactions
APIs make up the primary ingredients within drugs and are mostly responsible for drug-drug interactions. These drug-drug reactions constitute one of the major causes of failed treatment in patients as well as the production of adverse drug effects in them. Also, reactions of APIs combined within the same drug pose a significant challenge to API manufacturers and the healthcare industry.
How do API and drug interactions occur?
API and drug interactions usually occur as a result of poly-therapy, and this is mostly seen amongst elderly patients. With poly-therapy, the API of one drug interferes with the pharmacological activity of another, by enhancing or inhibiting the function of the other. These reactions usually result in diverse severe health implications and some scenarios, death. This interaction is significantly influenced by the pharmacodynamics of the body and the pharmacokinetics of the drug.
API and drug interaction can either occur during absorption, distribution, metabolism, or excretion of the drugs. Co-administration of drugs (polytherapy) greatly influences the body's response to them, and the risk of API and drug interaction rises as the number of medications administered increases. These reactions are why the API of drugs is taken into consideration when administering several drugs at once or concomitantly.
How does drug data sharing work?
The increasing need for transparency between research participants, publishers, research funders, pharmaceutical companies, regulating bodies, and trading companies during clinical trials has heightened the demand for drug data sharing. Though not yet fully established in some countries, several data sharing policies and guidelines have been set up to support this movement.
Through drug data sharing, clinical results, data, and clinical trial practices are shared and made available to pharmaceutical companies, research investigators, institutions, and other sectors to improve public health, drug development, and boost patient safety. Clinical data is shared at participant and company-level to improve company practices and public trust.
How do you set up the testing parameters of API reactions?
API testing ensures the production of stable and quality active pharmaceutical ingredients. The strength, quality, and stability of APIs are assessed by the manufacturers and regulating agencies through specific standards. Although this is done for all APIs, the testing parameters set up will vary based on the API and the brand. The primary test carried out is the stability test, and it includes stress-testing, storage conditions testing frequency, container closure system, specification, and selection of batches.
The quality of an API is directly proportional to the potency, efficacy, and safety of the medication. Low quality and compromised APIs harm the recipient's health. To ensure the production of high-quality and stable APIs, pharmaceutical companies are only allowed to handle one or two stages of the drug production process. Also, outsourced APIs and locally produced APIs and medications are thoroughly screened and tested to ensure the quality and safety of drugs.
What role does an API manufacturer play in pharmaceutical research?
The API manufacturers constitute a significant part of the pharmaceutical company globally, as well as the healthcare industry. They help to improve and facilitate pharmaceutical research in many ways. API manufacturers play a significant role in pharmaceutical research by conducting research and providing fact-based data and results on APIs and their pharmacological effects on the body.
Through in-depth analysis and a combination of efforts and contributions from active pharmaceutical ingredients manufacturers and other professionals in the pharmaceutical industry, potent and safer drugs can be developed to improve healthcare delivery.
What are the key market trends in API manufacturing?
The global demand for active pharmaceutical ingredients is on the rise, and there are a variety of factors that have actively contributed to its growth. Some of the key trends driving the development of the global active pharmaceutical ingredient market and API manufacturing include the worldwide rise of chronic diseases as well as the increasing demand for and importance of generics. Over the years, there's been a growing prevalence of chronic diseases such as chronic obstructive pulmonary disease (COPD), arthritis, hepatitis, cancer, etc., in various parts of the world.
The rapid rise of these diseases can be attributed to the increase in the geriatric population across the world. With this population experiencing a lifestyle change, and dietary consumption as a result of urbanization, an increase in the occurrence of chronic diseases such as cancer, is expected. This, in turn, will affect demand, as well as positively influence the market.
Also, as a result of technological advancement in active pharmaceutical ingredient manufacturing, the global API market is taking a huge turn around. Besides, another key trend that has positively influenced the market is the increased use of artificial intelligence-based drug discovery and production.
Market trends that have negatively influenced the global API manufacturing market include the cost of drug monitoring in other countries, intense competition between API manufacturers, and increasing production of anti-counterfeit drugs. The major market trend that has negatively influenced the market is the high cost of manufacturing APIs and unfavourable drug pricing control policies in countries across the world.
What are the key players in the active pharmaceutical ingredients market?
There are several competitor pharmaceutical companies working in the global active pharmaceutical ingredients market. These API manufacturing companies have contributed a great deal to the growth of the global API market. Some of the prominent and leading API companies include:
- Pfizer Inc. (US),
- TAPI (Teva Active Pharmaceutical Ingredients Israel),
- Sun Pharmaceutical Industries Ltd. (India),
- Aurobindo (India),
- Novartis International AG (Switzerland),
- Boehringer Ingelheim (Germany),
- Abbott (US),
- AbbVie (US),
- GlaxoSmithKline Plc (UK),
- Merck &Co. Inc. (US) amongst many others.
Regardless of these strategies, these key players in the global API market are still likely to face tough competition from new and upcoming companies in the industry.
References
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